Pure Autonomic Failure (PAF)

General Information

Vanderbilt University Autonomic Dysfunction Center:
http://www.mc.vanderbilt.edu/root/vumc.php?site=adc&doc=4790

Parkinsonian Disorders and Pure Autonomic failure:
http://www.wfneurology.org/pdfs/SeminarsInClinicalNeurology/Munsat_chapter8.pdf

Primary Autonomic Failure: Three Clinical Presentations of One Disease? by Horacio Kaufmann:
http://www.mssm.edu/neurology/autodis/disorders/parkinson/Primary.pdf

A Review of the Classification, Diagnosis, and Management of Autonomic Dysfunction Syndromes Associated with Orthostatic Intolerance by Blair P. Grubb and Sergio do Carmo Jorge:
http://publicacoes.cardiol.br/abc/2000/7406/74060008i.pdf

Identification of a Renin Threshold and Its Relationship to Salt Intake in a Patient With Pure Autonomic Failure by Henriette Hohenbleicher; Fabian Klosterman; Ulrike Schorr;Sepp Seyfert; Pontus B. Persson and Arya M. Sharma:
http://hyper.ahajournals.org/cgi/content/full/30/5/1068

Orthostatic Tolerance, Cerebral Oxygenation, and Blood Velocity in Humans With Sympathetic Failure by Harms M. P., Colier W. N., Wieling W., Lenders J. W., Secher N. H., van Lieshout J. J.:
http://stroke.ahajournals.org/cgi/content/full/31/7/1608

Fear Conditioning in Humans: The Influence of Awareness and Autonomic Arousal on Functional Neuroanatomy by Hugo D. Critchley, Christopher J. Mathias, Raymond J. Dolan:
http://www.psychiatry.wustl.edu/Resources/LiteratureList/2002/February/
Critchley.pdf

Medical Physiology CV Conference 2, Q & A
http://www3.kumc.edu/aamsa/subjects/Phys/conference/2000/cv2.pdf

Causes/Mechanisms

The Distribution of Lewy Bodies in Pure Autonomic Failure: Autopsy Findings and Review of the Literature by K. Hague, P. Lento, S. Morgello, S. Laro and H. Kaufmann:
http://www.springerlink.com/content/cm7nrxyrh9lru35j/fulltext.pdf?page=1

Accumulation of Alpha Synuclein in Autonomic Nerves in Pure Autonomic Failure by Horacio Kaufmann, Karen Hague and Daniel Perl:
http://www.mssm.edu/neurology/autodis/disorders/paf/Synuclein.pdf

Hypotension and/or Hypertension

Stress induced hypotension in pure autonomic failure by R D Thijs and J G van Dijk:
http://jnnp.bmjjournals.com/cgi/content/abstract/77/4/552

Orthostatic Hypotension by Bradley JG, Davis KA.
http://www.aafp.org/afp/20031215/2393.pdf

Autoregulation of Cerebral Blood Flow in Orthostatic Hypotension by Novak V., Novak P., Spies J. M., Low P. A.:
http://stroke.ahajournals.org/cgi/content/full/29/1/104

Idiopathic Orthostatic Hypotension and other Autonomic Failure Syndromes by Dianna Quan:
http://www.emedicine.com/neuro/topic609.htm

Neck and other muscle pains in autonomic failure: their association with orthostatic hypotension by K M Bleasdale-Barr and C J Mathias:
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1296807&blobtype=pdf

Cognitive functioning in orthostatic hypotension due to pure autonomic failure by Heims HC, Critchley HD, Martin NH, Jager HR, Mathias, CJ, Cipolotti L.:
http://www.ncbi.nlm.nih.gov/pubmed/16683070

Sympathetically Mediated Hypertension in Autonomic Failure by John R. Shannon, Jens Jordan, Andre Diedrich, Bojan Pohar, Bonnie K. Black,
David Robertson, Italo Biaggioni:
http://circ.ahajournals.org/cgi/content/abstract/101/23/2710?ck=nck

Vasopressin and Blood Pressure in Humans by Jens Jordan and Jens Tank:
http://hyper.ahajournals.org/cgi/content/full/36/6/e3

Outlook

Progression and prognosis in pure autonomic failure (PAF): comparison with multiple system atrophy by N Mabuchi, M Hirayama, Y Koike, H Watanabe, H Ito, R Kobayashi,K Hamada and G Sobue:
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1739727&blobtype=pdf

Sleep

A Sound Night’s Rest may do no good in Autonomic Failure! by Christopher J. Mathias:
http://cs.portlandpress.co.uk/cs/101/0619/1010619.pdf

Tests

Hormonal and cardiovascular reflex assessment in a female patient with pure autonomic failure by Lopes HF, Consolim-Colombo FM, Hachul D, Carvalho ME, Pileggi F, Silva HB:
http://www.scielo.br/pdf/abc/v75n3/2870.pdf

Evaluation of orthostatic hypotension: relationship of a new self-report
instrument to laboratory-based measures
by Schrezenmaier C, Gehrking JA, Hines SM, Low PA, Benrud-Larson LM, Sandroni P:
http://www.mayoclinicproceedings.com/content/80/3/330

Treatments

Could treatment with DOPS do for autonomic failure what DOPA did for Parkinson’s disease by Horacio Kauffman:
http://www.mountsinai.org/img/vgn_lnk/Regular%20Content/File/Research/Autonomic%20Disorders%20Program/DOPS.pdf

The Anemia of Primary Autonomic Failure and its Reversal with Recombinant Erythropoietin by Italo Biaggioni, David Robertson, Sanford Krantz, Mark Jones,  and Virginia Haile:
http://www.acponline.org/journals/annals/01aug94/anemia.htm

The Pressor Response to Water Drinking in Humans by Jens Jordan, John R. Shannon, Bonnie K. Black, Yasmine Ali, Mary Farley;Fernando Costa, Andre Diedrich, Rose Marie Robertson, Italo Biaggioni and
David Robertson:
http://circ.ahajournals.org/cgi/content/full/101/5/504

The Hypertension of Autonomic Failure and its Treatment by John Shannon, Jens Jordan, Fernando Costa, Rose Marie Robertson, and Italo Biaggioni:
http://hyper.ahajournals.org/cgi/content/abstract/30/5/1062